Where Biology Meets Technology
STAR – Signal Transduction, Activity and Response – Drug Discovery Platform fast tracks the design of sophisticated multi-target medicines that map to complex disease biology.
STAR utilizes bioinformatics and multi-omics technologies and gives insights on how to
- Improve efficacy by designing synergistic mechanisms of action
- Improve safety by predicting and avoiding off-target toxicities and drug resistance
First-in-Class Medicines, powered by Nature
New regulatory pathways for botanical drugs create new opportunities for developing multi-targeted botanical mixtures as prescription medicines. YIV-906 is a proof of concept platform drug with supporting evidence from 260 patients across 9 trials (HCC, pancreatic, colorectal, rectal). Formerly known as PHY-906/KD018, YIV-906 is the first drug that could potentiate anti tumor activity and reduce treatment toxicity when combined with standard of care.
Yiviva has developed core CMC (Chemistry, Manufacturing, and Controls) Platforms to modernize botanical medicines and ensure consistency:
- Mech QC – Mechanism-based Quality Control is a validated platform utilizing clinically-relevant bioassays, bio-response fingerprinting, and similarity index methodology to manufacture batch-to-batch, consistent complex mixtures
- SMART – Symbiotic Microbiota for Agriculture Resource and Technology is a proprietary AgTech natural resource platform to scale bioactive medicinal plants.
Scientist examining samples with plants,Closeup